MyBioSource.com's ATP2A2 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The ATP2A2 Antibody (Center) was generated using ATP2A1, ATP2A2, ATP2B, and SERCA2B as the antigen and it reacts with Human.
Description
This gene encodes one of the SERCA Ca(2+)-ATPases, which
are intracellular pumps located in the sarcoplasmic or endoplasmic
reticula of muscle cells. This enzyme catalyzes the hydrolysis of
ATP coupled with the translocation of calcium from the cytosol into
the sarcoplasmic reticulum lumen, and is involved in regulation of
the contraction/relaxation cycle. Mutations in this gene cause
Darier-White disease, also known as keratosis follicularis, an
autosomal dominant skin disorder characterized by loss of adhesion
between epidermal cells and abnormal keratinization. Alternative
splicing results in multiple transcript variants encoding different
isoforms